Peptide Database

Peptide NameBeta_Defensin-CohPH-6

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC375H578N98O92S8

DescriptionStandard

        MKILYLLFAFLFLAFLSEPGNAYKRCHKKGGHCFPKEKICIPPSSDFGKMDCRWKWKCCKREVENNAISI
    

Molecular Weight8187.72 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)6.62

Net Charge (pH 7.4) 6.19

Charge Density (pH 7.0) 0.0945

GRAVY Index-0.20

Hydrophobic Moment 0.59

Boman Index0.00

Instability Index53.52

Aliphatic Index 71.14

Aromaticity 0.1429

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3045.35

LogP -19.46

H-bond Donors 111.0

H-bond Acceptors 109.0

Rotatable Bonds 272.0

Heavy Atoms 573.0

Ring Count 18.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0159730 VERIFIED: YES

Provenance & Taxonomy

OrganismCrotalus oreganus [Animal]

FamilyDefensin

Tax ID332624

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Toxin Non-hemolytic Non-ribosomal