Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length188 amino acids

Chemical FormulaC893H1380N220O258S8

DescriptionStandard

        MTAIDAMAGIDYSLVAPPAATAQSLDVDLKGEFFSLAHRSAVPFPPLALALPPDHDRMVYFGASSYFFNTASVAYHAAGALVLDITNSIPKDVEFHLNTSTFSAFVPQVSAWPCLPIMKVRLSTPSAPFLTIGPDGLSLRPVVDIQTYAILPNSTLAPLFLLSLVSCDCGSVGAAQGAPTASAAAVCP
    

Molecular Weight19582.35 Da

Isoelectric Point (pI)4.82

Net Charge (pH 7.0)-6.18

Net Charge (pH 7.4) -6.68

Charge Density (pH 7.0) -0.0329

GRAVY Index0.53

Hydrophobic Moment 0.57

Boman Index0.29

Instability Index35.29

Aliphatic Index 98.72

Aromaticity 0.0904

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13200.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7331.85

LogP -83.18

H-bond Donors 250.0

H-bond Acceptors 264.0

Rotatable Bonds 593.0

Heavy Atoms 1379.0

Ring Count 41.0

Amide Bonds 195.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096997 VERIFIED: NO

Provenance & Taxonomy

OrganismMelopsittacus undulatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence