Peptide Database

Peptide Namealpha-Glia AG12 (p82p98; E90)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC92H131N21O26

DescriptionStandard

        PQPQPFPPELPYPQPQS
    

Molecular Weight1947.15 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.04

Net Charge (pH 7.4) -1.10

Charge Density (pH 7.0) -0.0612

GRAVY Index-1.52

Hydrophobic Moment 0.22

Boman Index-0.05

Instability Index177.36

Aliphatic Index 22.94

Aromaticity 0.1176

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 703.52

LogP -5.72

H-bond Donors 18.0

H-bond Acceptors 25.0

Rotatable Bonds 48.0

Heavy Atoms 139.0

Ring Count 10.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0121172 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E90

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay