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MYP_057608
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Basic Information
RNST-2-14K
Anticancer
Antimicrobial
Antimicrobial ▸ Antifungal
Standard
14 amino acids
C74H122N16O16S
Standard
Sequence
FLKGLMGVIASLFK
Physicochemical Analysis
1523.92 Da
10.00
1.76
1.55
0.1256
1.43
0.42
0.50
-13.58
139.29
0.1429
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
513.89
-0.69
18.0
19.0
52.0
107.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0311324 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is unique and shows only very low similarity (60%) to Lausporin-1 L:21%, G=K=F: Chemical modification: A10: D-amino acid; C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
human RBC: HC50 51 uM. Hemolytic. Breast cancer cells MCF-7
42.7 μM
IC50
PaperSynthesis of Temporin-SHa Retro Analogs with Lysine Addition/Substitution and Antibiotic Conjugation to Enhance Antibacterial, Antifungal, and Anticancer Activities.
RECORD: Rec_0372206 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is unique and shows only very low similarity (60%) to Lausporin-1 L:21%, G=K=F: Chemical modification: A10: D-amino acid; C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
cervical cancer Hela cells
33.5 μM
IC50
PaperSynthesis of Temporin-SHa Retro Analogs with Lysine Addition/Substitution and Antibiotic Conjugation to Enhance Antibacterial, Antifungal, and Anticancer Activities.
RECORD: Rec_0409084 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is unique and shows only very low similarity (60%) to Lausporin-1 L:21%, G=K=F: Chemical modification: A10: D-amino acid; C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
fungi Candida albicans ATCC 36082
15.6 μM
MIC
PaperSynthesis of Temporin-SHa Retro Analogs with Lysine Addition/Substitution and Antibiotic Conjugation to Enhance Antibacterial, Antifungal, and Anticancer Activities.
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