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MYP_057586
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Basic Information
Tyrocidine B
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
FPWFNQYVXL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0209104 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
tyrocidine
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Non-proteinogenic/modified monomers: Orn
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0229428 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Aspergillus fumigatus ATCC 204305
2.5 μM
IC50
PMID24752256;17462586;27328781;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24752256/
RECORD: Rec_0231634 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Micrococcus luteus NCTC 8340
9.9 μM
MIC
PMID24752256;17462586;27328781;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24752256/
RECORD: Rec_0272474 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 9
Bio-Activity Profile
Hemolytic
human red blood cells
2.6 μM
HC50
PMID24752256;17462586;27328781;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24752256/
RECORD: Rec_0298216 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Listeria monocytogenes B73-MR1
7.7 μM
IC50
PMID24752256;17462586;27328781;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24752256/
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