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MYP_057585
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Basic Information
Caenacin-4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Standard
48 amino acids
C236H329N57O60S6
Standard
Sequence
QWGYGPYGGYGGGYPGMYGGYGMRPYGMYGGYGMGMYRPGLLGMLIGK
Physicochemical Analysis
5116.87 Da
9.35
2.75
2.53
0.0573
-0.35
0.27
0.29
16.02
32.50
0.2292
20400.00
20400.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1806.86
-11.96
64.0
69.0
154.0
359.0
16.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0151353 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
Caenacin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis ATCC29212
PMID34184732 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34184732/
RECORD: Rec_0152419 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
Caenacin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis ATCC12228
PMID34184732 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34184732/
RECORD: Rec_0157376 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
Caenacin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
PMID34184732 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34184732/
RECORD: Rec_0175943 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 20.8%, E 4.2%, T 35.4%, C 39.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0184339 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
But salt-sensitive to 150 mM or 300 mM NaCl
>64 μM
MBC
PaperTLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.
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