‹ ›
MYP_057559
← PREVIOUS NEXT → BACK
Basic Information
Phylloseptin-L1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C84H151N19O22S
Standard
Sequence
LLGMIPLAISAISALSKL
Physicochemical Analysis
1811.28 Da
8.75
0.76
0.55
0.0422
1.75
0.40
0.58
3.13
190.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
635.94
-2.94
22.0
24.0
60.0
126.0
1.0
17.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0061570 VERIFIED: YES
Provenance & Taxonomy
Agalychnis lemur [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Anticancer Hemolytic
Batrachochytrium dendrobatidis
PMID17561225;18644413 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17561225/
RECORD: Rec_0081708 VERIFIED: YES
Provenance & Taxonomy
Hylomantis lemur [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
HepG2 cells
35 μM
LC50
PaperPeptides with differential cytolytic activity from skin secretions of the lemur leaf frog Hylomantis lemur (Hylidae: Phyllomedusinae).
RECORD: Rec_0084542 VERIFIED: YES
Provenance & Taxonomy
Hylomantis lemur [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus
8 μg/mL
MIC
PaperPeptides with differential cytolytic activity from skin secretions of the lemur leaf frog Hylomantis lemur (Hylidae: Phyllomedusinae).
RECORD: Rec_0091000 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the lemur leaf frog Hylomantis lemur [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
200 μM
LC50
PaperPubMed PMID: 17561225 PMID17561225 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17561225/
RECORD: Rec_0092055 VERIFIED: YES
Provenance & Taxonomy
Agalychnis callidryas [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Antibacterial Anti-Gram-positive
Staphylococcus aureus
8 μg/mL
MIC
FIRST PREV 1 2 3 4 ... 7 NEXT LAST
Showing 5 records on this page · Page 2 of 7