Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC425H682N120O123S13

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAIPFTGVQELEEAGSNDTPVVAHQEMSVESSMMPNHIRQKRQSHLSLCRWCCKCCRNKGCGFCCKF
    

Molecular Weight9857.54 Da

Isoelectric Point (pI)8.11

Net Charge (pH 7.0)1.69

Net Charge (pH 7.4) 1.17

Charge Density (pH 7.0) 0.0189

GRAVY Index0.21

Hydrophobic Moment 0.72

Boman Index0.09

Instability Index65.10

Aliphatic Index 78.88

Aromaticity 0.0674

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3882.77

LogP -40.32

H-bond Donors 143.0

H-bond Acceptors 141.0

Rotatable Bonds 328.0

Heavy Atoms 681.0

Ring Count 13.0

Amide Bonds 95.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0318663 VERIFIED: NO

Provenance & Taxonomy

OrganismAmphilophus citrinellus [Bacterium]

FamilyHepcidin

Tax ID61819

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal