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MYP_057529
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Basic Information
Decoralin [AT2]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
11 amino acids
C64H121N15O13
Standard
Sequence
TLLLLIRKLIL
Physicochemical Analysis
1308.74 Da
11.00
1.40
1.21
0.1270
2.06
0.41
0.46
18.88
283.64
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
462.47
1.39
17.0
15.0
46.0
92.0
0.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046582 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HDMEC
348±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0150141 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
A549
79±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0159790 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
38±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0200982 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Jurkat
30±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0215647 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: 1205Lu
16±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
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