Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitor

Function Ontology

Enzyme modulation ▸ Enzyme inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC47H75N15O18

DescriptionStandard

        AGPPGSDGQPGAK
    

Molecular Weight1138.19 Da

Isoelectric Point (pI)5.88

Net Charge (pH 7.0)-0.20

Net Charge (pH 7.4) -0.39

Charge Density (pH 7.0) -0.0157

GRAVY Index-1.12

Hydrophobic Moment 0.28

Boman Index0.01

Instability Index32.33

Aliphatic Index 15.38

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 512.79

LogP -8.84

H-bond Donors 15.0

H-bond Acceptors 18.0

Rotatable Bonds 32.0

Heavy Atoms 80.0

Ring Count 3.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052977 VERIFIED: YES

Provenance & Taxonomy

OrganismSynodus macrops [Animal]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity420±20 μM

MethodIC50