Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length243 amino acids

Chemical FormulaC1260H1898N280O362S9

DescriptionStandard

        IDDLAEIDYSLNSLPAVFRPFIDLDLKGIVYPAGNYSGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTCSFAYYTAGAFNITIAEEVKSGKLFYLFFFFLQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTAEIQGSMEVFAVLPDSTTHSLFTMNIAANTSIALNIFDQKLMGSLCLNRLQFSLTHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight27048.79 Da

Isoelectric Point (pI)4.32

Net Charge (pH 7.0)-13.07

Net Charge (pH 7.4) -13.48

Charge Density (pH 7.0) -0.0538

GRAVY Index0.40

Hydrophobic Moment 0.60

Boman Index0.28

Instability Index46.77

Aliphatic Index 99.59

Aromaticity 0.1481

Extinction Coeff. Reduced 19370.00

Extinction Coeff. Oxidized 19495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0391497 VERIFIED: NO

Provenance & Taxonomy

OrganismFulmarus glacialis [other]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria