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MYP_057510
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Basic Information
[β-Ala8]H2-(7-15)
Antimicrobial
Antiviral
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
YXGAVVNDL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0153317 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
The 'X' at position 2 is 3-aminoproprionic acid
Bio-Activity Profile
Antimicrobial Antiviral
Herpes simplex virus type 1:inhibition of HSV-1 ribonucleotide reductase activity
100 μM
IC50
PaperPubMed PMID: 3040743 PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
RECORD: Rec_0251260 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
The 'X' at position 2 is 3-aminoproprionic acid
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 3040743 PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
RECORD: Rec_0343697 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
stereochemistry not specified [Other]
None
None
The 'X' at position 2 is 3-aminoproprionic acid.
Bio-Activity Profile
Antiviral
Herpes simplex virus type 1
100 μM
IC50
Mammalian: 2.8 h; Yeast: 10 min; E. coli: 2 min
PaperStructure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase. | Gaudreau P, Michaud J, Cohen EA, Langelier Y, Brazeau P. | J Biol Chem. 1987 Sep 15;262(26):12413-6. | DOI:Not available | PMID:3040743 PMID3040743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3040743/
RECORD: Rec_0393682 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 55.6%, C 44.4% [Linear]
D-residue-containing modified peptide [Mixed]
Acetylation
None
Ac : Acetyl, (A) : D-Alanine
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0413287 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 66.7%, C 33.3% [Linear]
D-residue-containing modified peptide [Mixed]
None
None
(A) : D-Alanine
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/