Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length474 amino acids

Chemical FormulaC2411H3762N622O680S14

DescriptionStandard

        MRRVSLLVFWLGCLVPSSEGVNPGFAGRITRKGLDYACQEGVATLRKDLPAIILPEFSGTYRVKIIGNVNYRFYRLNFRRFELFHSTIEPMPGQGLRVSISNALAEMTGHWELKKRWLKDDGSFELKVDGISISVGLKLGSDATGRPTVTTLDCNTHISNVDIDISGKWEWLYNLFETKVESAFKTVMESKICEIVRTSINSKLQPHLQSLPVTANIDHTSNIDYSLVGPPVATSDCVDLDLKGEFFSTGHRSPAPFPPPPLSFPVDHDRMVQFGISTYFFNTAGDVYYKAESLTFWVVDEMVPQEIKIRLNTSSFQPFIPQLKKLYHNMPMKLKVSPSSAPSLSITPETLSLTPSVDIQAFAILPNSFLAPLFLIGVTSPVSAKVAVNSTRIFGNLKLGRLKFSLKHSDVGFFSVQVLESLINFLTASILIPQMNARLAEGFPLPLLDHLELSNPILQAHQDFLVFASDVRYG
    

Molecular Weight52790.33 Da

Isoelectric Point (pI)7.69

Net Charge (pH 7.0)1.46

Net Charge (pH 7.4) 0.51

Charge Density (pH 7.0) 0.0031

GRAVY Index0.05

Hydrophobic Moment 0.71

Boman Index0.12

Instability Index39.06

Aliphatic Index 97.03

Aromaticity 0.1013

Extinction Coeff. Reduced 49390.00

Extinction Coeff. Oxidized 49640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0179349 VERIFIED: NO

Provenance & Taxonomy

OrganismPantherophis guttatus (Corn snake) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria