Peptide Database

Peptide NameSyn-larvacin-51

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC145H230N40O32

DescriptionStandard

        AGKETIFWRLKKKIWEKGKRATIAW
    

Molecular Weight3045.63 Da

Isoelectric Point (pI)10.66

Net Charge (pH 7.0)5.80

Net Charge (pH 7.4) 5.59

Charge Density (pH 7.0) 0.2318

GRAVY Index-0.75

Hydrophobic Moment 0.70

Boman Index-0.16

Instability Index5.66

Aliphatic Index 74.40

Aromaticity 0.1600

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1204.07

LogP -5.25

H-bond Donors 45.0

H-bond Acceptors 38.0

Rotatable Bonds 105.0

Heavy Atoms 217.0

Ring Count 7.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0189481 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity<20 μM

MethodCC50

RECORD: Rec_0250897 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity0.42 μM

MethodIC50