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MYP_057447
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Basic Information
GHaR9W (variant of temporin-GHaR)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
13 amino acids
C74H119N21O15
Standard
Sequence
FLQRIIGAWGRLL
Physicochemical Analysis
1542.87 Da
12.00
1.76
1.56
0.1354
0.83
0.76
0.28
19.80
157.69
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
595.20
-1.51
22.0
17.0
50.0
110.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0128159 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human red blood cells (hRBCs)
PaperTemporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis PMID33291521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33291521/
RECORD: Rec_0166889 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli ATCC 25922
12.5 μM
MIC
PaperTemporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis PMID33291521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33291521/
RECORD: Rec_0189289 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa ATCC 15442
>50 μM
MIC
PaperTemporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis PMID33291521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33291521/
RECORD: Rec_0222397 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
methicillin-resistant Staphylococcus aureus ATCC 43300
6.2 μM
MIC
PaperTemporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis PMID33291521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33291521/
RECORD: Rec_0222907 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa PAO1
25 μM
MIC
PaperTemporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis PMID33291521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33291521/
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