‹ ›
MYP_057362
← PREVIOUS NEXT → BACK
Basic Information
Clavanin-B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
23 amino acids
C131H184N36O27
Standard
Sequence
VFQFLGRIIHHVGNFVHGFSHVF
Physicochemical Analysis
2695.09 Da
9.75
1.08
0.67
0.0471
0.75
0.72
0.42
-6.77
101.30
0.2174
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
986.55
-4.81
34.0
32.0
83.0
194.0
9.0
24.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0290673 VERIFIED: NO
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPatent US 10723764 B2 Evidence URLhttps://patents.google.com/patent/US10723764B2/en PatentUS 10723764 B2
RECORD: Rec_0296334 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Human immunodeficiency virus 1 (HIV-1)
7.1 μM
EC50
PaperClavanins, alpha-helical antimicrobial peptides from tunicate hemocytes.
RECORD: Rec_0323035 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
7725
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV-1 Entry inhibition
HIV-1 IIIB | CEM-SS cells
7.1 μM
EC50
Mammalian: 100 h; Yeast: >20 h; E. coli: >10 h
PaperIdentification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr. | Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6. | DOI:10.1128/AAC.01448-09 | PMID:20086159 PMID20086159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20086159/
RECORD: Rec_0323535 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperLee I.H., Zhao C., Cho Y., Harwig S.S.L., Cooper E.L., Lehrer R.I.;. "Clavanins, alpha-helical antimicrobial peptides from tunicate hemocytes."; FEBS Lett. 400:158-162(1997). Evidence URLhttps://www.uniprot.org/uniprotkb/CLVB_STYCL/entry
RECORD: Rec_0373531 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
monocytes
PaperPubMed PMID: 9001389 PMID9001389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9001389/
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records on this page · Page 4 of 5