Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC158H236N40O41S2

DescriptionStandard

        QAVLPPQHLCGAHLVDALYLVCGERGFFYTP
    

Molecular Weight3415.94 Da

Isoelectric Point (pI)5.99

Net Charge (pH 7.0)-1.08

Net Charge (pH 7.4) -1.42

Charge Density (pH 7.0) -0.0349

GRAVY Index0.43

Hydrophobic Moment 0.30

Boman Index0.29

Instability Index20.60

Aliphatic Index 100.65

Aromaticity 0.1290

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1250.68

LogP -7.70

H-bond Donors 43.0

H-bond Acceptors 44.0

Rotatable Bonds 101.0

Heavy Atoms 241.0

Ring Count 9.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0180932 VERIFIED: NO

Provenance & Taxonomy

OrganismVerasper moseri [Animal]

FamilyInsulin

Tax ID98923

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0274814 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0322350 VERIFIED: NO

Provenance & Taxonomy

OrganismVerasper moseri [Animal]

FamilyInsulin

Tax ID98923

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour