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MYP_057338
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Basic Information
A1P394-428
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
35 amino acids
C194H308N50O44S2
Standard
Sequence
PPPVIKFNRPFLMWIVERDTRSILFMGKIVNPKAP
Physicochemical Analysis
4108.96 Da
11.00
3.96
3.90
0.1131
0.02
0.54
0.08
43.54
94.57
0.1143
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1475.57
-6.67
50.0
50.0
128.0
290.0
11.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0234208 VERIFIED: YES
Provenance & Taxonomy
Alligator mississippiensis [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
0.0986 μM
EC50
PaperBioprospecting the American Alligator (Alligator mississippiensis) Host Defense Peptidome.
RECORD: Rec_0240402 VERIFIED: YES
Provenance & Taxonomy
American alligator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
A549 human lung epithelial cells
Cell viability assay
PMID27542832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27542832/
RECORD: Rec_0248557 VERIFIED: YES
Provenance & Taxonomy
American alligator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC BAA-1718
36.5 μg/mL
EC50
PMID27542832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27542832/
RECORD: Rec_0259926 VERIFIED: YES
Provenance & Taxonomy
Alligator mississippiensis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii ATCC BAA-1794
2.36 μg/mL
EC50
PMID27542832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27542832/
RECORD: Rec_0275756 VERIFIED: YES
Provenance & Taxonomy
American alligator [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID25671663 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25671663/
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