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MYP_057338
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Basic Information
A1P394-428
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
35 amino acids
C194H308N50O44S2
Standard
Sequence
PPPVIKFNRPFLMWIVERDTRSILFMGKIVNPKAP
Physicochemical Analysis
4108.96 Da
11.00
3.96
3.90
0.1131
0.02
0.54
0.08
43.54
94.57
0.1143
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1475.57
-6.67
50.0
50.0
128.0
290.0
11.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0117376 VERIFIED: YES
Provenance & Taxonomy
American alligator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
Not hemolytic to sheep red blood cells
PMID27542832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27542832/
RECORD: Rec_0120362 VERIFIED: YES
Provenance & Taxonomy
Alligator mississippiensis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
38.6 μg/mL
EC50
PMID27542832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27542832/
RECORD: Rec_0155184 VERIFIED: YES
Provenance & Taxonomy
Alligator mississippiensis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii ATCC 9955
24.0 μg/mL
EC50
PMID27542832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27542832/
RECORD: Rec_0166462 VERIFIED: YES
Provenance & Taxonomy
Alligator mississippiensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
00986 μM
EC50
RECORD: Rec_0180676 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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