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MYP_057334
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Basic Information
Murepavadin [T1L,W2S,I3Y,DAB10tBuGly]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
LSYXXXXWXXASPP
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0357791 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 4,5,6,7,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Enterobacter spp.
4 μg/mL
MIC50
PMID31645764 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31645764/
RECORD: Rec_0358940 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 4,5,6,7,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii AL1851-DelLpxA
2 μg/mL
MIC
PMID31645764 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31645764/
RECORD: Rec_0369008 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 4,5,6,7,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
8 μg/mL
MIC50
PMID31645764 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31645764/
RECORD: Rec_0378028 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 4,5,6,7,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii ATCC 19606
2 μg/mL
MIC
PMID31645764 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31645764/
RECORD: Rec_0394259 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 4,5,6,7,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
0.5 μg/mL
MIC
PMID31645764 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31645764/
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