Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length200 amino acids

Chemical FormulaC1017H1594N268O272S10

DescriptionStandard

        PKTLPMAHEPMLLLAVTEFVANSAAFTYFTAGALSRNISSDMLPQQFPLQLRTKSMEVFSPQLQERYPDQPMELHLWAHRQPLISCHPDALHGTLFSSAEAFVVLPNATRVPVFLLNIDANMTGKPTITRNRLGGTVRLTGLVPDPELVLPSLWTPLFALCWAQGLPVPQVKRLETLLKFGLWLFGVPRANSECCPRPVP
    

Molecular Weight22247.82 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)2.38

Net Charge (pH 7.4) 1.98

Charge Density (pH 7.0) 0.0119

GRAVY Index0.10

Hydrophobic Moment 0.54

Boman Index0.14

Instability Index55.04

Aliphatic Index 96.55

Aromaticity 0.0850

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8422.26

LogP -101.60

H-bond Donors 287.0

H-bond Acceptors 289.0

Rotatable Bonds 694.0

Heavy Atoms 1567.0

Ring Count 49.0

Amide Bonds 215.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0381570 VERIFIED: NO

Provenance & Taxonomy

OrganismPardalotus punctatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria