Peptide Database

Peptide NameSLAY-screened peptide P157

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC124H158N36O27S

DescriptionStandard

        AGGYRHYMYGPHDWRFHRFY
    

Molecular Weight2616.87 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)2.05

Net Charge (pH 7.4) 1.71

Charge Density (pH 7.0) 0.1027

GRAVY Index-1.31

Hydrophobic Moment 0.41

Boman Index-0.13

Instability Index80.44

Aliphatic Index 5.00

Aromaticity 0.3500

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1013.18

LogP -5.05

H-bond Donors 38.0

H-bond Acceptors 33.0

Rotatable Bonds 75.0

Heavy Atoms 188.0

Ring Count 12.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0360788 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/