Peptide Database

Peptide NameDQ2-Glia-alpha1 epitope (p58p72; S64 and S69)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC81H120N20O24

DescriptionStandard

        LQPFPQSQLPYSQPQ
    

Molecular Weight1757.94 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0161

GRAVY Index-1.09

Hydrophobic Moment 0.20

Boman Index-0.04

Instability Index175.92

Aliphatic Index 52.00

Aromaticity 0.1333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 711.70

LogP -7.19

H-bond Donors 20.0

H-bond Acceptors 24.0

Rotatable Bonds 50.0

Heavy Atoms 125.0

Ring Count 6.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010456 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsReported substitutions/positions: S64; Reported substitutions/positions: S69

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay