Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC170H272N50O56S2

DescriptionStandard

        KCNTATCVTQRLADFLVRSSSHIGAIYSPTNVGSNTY
    

Molecular Weight3976.41 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.54

Charge Density (pH 7.0) 0.0493

GRAVY Index-0.10

Hydrophobic Moment 0.68

Boman Index0.03

Instability Index31.82

Aliphatic Index 73.78

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1733.05

LogP -24.32

H-bond Donors 64.0

H-bond Acceptors 61.0

Rotatable Bonds 126.0

Heavy Atoms 278.0

Ring Count 5.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0045196 VERIFIED: YES

Provenance & Taxonomy

OrganismAcanthisitta chloris [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)