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MYP_057289
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Basic Information
Sauvatide
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
10 amino acids
C53H99N17O12
Standard
Sequence
LRPAILVRTK
Physicochemical Analysis
1166.46 Da
12.00
2.76
2.55
0.2759
0.29
0.17
-0.13
86.04
156.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
486.48
-2.88
18.0
15.0
38.0
82.0
1.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042790 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
128 μg/mL
Hemolysis
PMID25054164 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25054164/
RECORD: Rec_0073134 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Sauvatide
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Smooth muscle contraction
PaperL. Wang et al. / BBRC 383 (2009) 240-244. Sauvatide--a novel amidated myotropic decapeptide from the skin secretion of the waxy monkey frog, Phyllomedusa sauvagei Evidence URLhttps://www.uniprot.org/uniprotkb/C5J8E3/entry
RECORD: Rec_0102931 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagei [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
induces contraction of smooth muscle in isolated rat urinary bladder
0.0022 μM
EC50
RECORD: Rec_0163681 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NCTC 10418
512 μg/mL
MIC
PMID25054164 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25054164/
RECORD: Rec_0214338 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
512 μg/mL
MIC
PMID25054164 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25054164/
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