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MYP_057273
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Basic Information
Magainin-2 [ins5L][S9A][G14A][G19A][I21K]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C122H196N32O29S
Standard
Sequence
GIGKLFLHAAKKFAKAFVAEKMNS
Physicochemical Analysis
2607.12 Da
10.18
3.85
3.58
0.1602
0.18
0.63
0.14
12.55
81.67
0.1250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
992.02
-6.47
34.0
35.0
91.0
184.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029862 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
100 μg/mL
MBC
PMID1605597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1605597/
RECORD: Rec_0047554 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 54.2%, E 0.0%, T 20.8%, C 25.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0047611 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
200 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/1605597/ PMID1605597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1605597/
RECORD: Rec_0080672 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
25 μg/mL
MBC
PMID1605597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1605597/
RECORD: Rec_0082392 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
6.25 μg/mL
MIC
PMID1605597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1605597/
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