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MYP_057197
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Basic Information
Unnamed
Antimicrobial
Antiviral
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunostimulatory activity
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Regulatory peptide ▸ Biological regulation
Standard
3 amino acids
C17H25N3O5
Standard
Sequence
LGY
Physicochemical Analysis
351.40 Da
5.52
-0.24
-0.45
-0.0803
0.70
0.28
0.60
-21.63
130.00
0.3333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
141.75
-0.01
5.0
5.0
9.0
25.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0268501 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
99130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
SARS-CoV-2 main protease
PaperViral 3CLpro as a target for antiviral intervention using milk-derived bioactive peptides. International Journal of Peptide Research and Therapeutics 27:2703-2716 (2021). PMID: 34548852. PMID34548852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34548852/
RECORD: Rec_0368074 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
Spontaneously hypertensive rats
PaperResistance of casein-derived bioactive peptides to simulated gastrointestinal digestion | Contreras, M. del Mar. et al. | DOI: 10.1016/j.idairyj.2013.05.008 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0380500 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunostimulatory
PaperXu R. J. Bioactive peptides in milk and their biological and health implications. Food. Rev. Int. 14, 1-16, 1998.
RECORD: Rec_0392607 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
21.46
IC50
PaperContreras M. M., S¨¢nchez-Infantes D., Sevilla M. A., Recio I., Amigo L.. Resistance of casein-derived bioactive peptides to simulated gastrointestinal digestion. Int. Dairy J., 32, 71-78, 2013.
RECORD: Rec_0394941 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Regulatory
PaperMigliore-Samour D., Roch-Arveiller M., Tissot M., Jazziri M., Keddad K., Giroud J-P., Jolles P.. Effects of tripeptides derived from milk proteins on polymorphonuclear oxidative and phosphoinositide metabolisms. Biochem. Pharmacol., 44, 673-680, 1992.
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