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MYP_057183
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C21H34N4O5
Standard
Sequence
LKY
Physicochemical Analysis
422.52 Da
8.59
0.76
0.55
0.2527
-0.47
0.63
-0.06
-21.63
130.00
0.3333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
167.77
0.49
6.0
6.0
13.0
30.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070652 VERIFIED: NO
Provenance & Taxonomy
Sesamum indicum [Plant]
ACE-inhibitory peptide
4182
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
0.33-5.8 μg/mL
IC50
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
RECORD: Rec_0084569 VERIFIED: NO
Provenance & Taxonomy
Euphausia superba [Animal]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
10.1 μM
IC50
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
RECORD: Rec_0214433 VERIFIED: NO
Provenance & Taxonomy
Sesamum indicum [Plant]
ACE-inhibitory peptide
4182
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive Antioxidant
Spontaneously hypertensive rat (SHR)
25 mmHg
SBP decrease
PaperVegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
RECORD: Rec_0223432 VERIFIED: YES
Provenance & Taxonomy
Sesamum indicum [Plant]; Euphausia superba [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Neuropeptide ACE inhibitory
Angiotensin-converting enzyme
0.78 μM
IC50
RECORD: Rec_0235413 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
6.11 pIC50
pIC50
PaperWhat are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach. PMID23871047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871047/
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