Peptide Database

Peptide NameScg-AKH-II

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC44H60N10O14

DescriptionStandard

        ELNFSTGW
    

Molecular Weight953.01 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.16

Net Charge (pH 7.4) -1.33

Charge Density (pH 7.0) -0.1454

GRAVY Index-0.40

Hydrophobic Moment 0.12

Boman Index0.22

Instability Index-5.22

Aliphatic Index 48.75

Aromaticity 0.2500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 403.66

LogP -3.45

H-bond Donors 14.0

H-bond Acceptors 13.0

Rotatable Bonds 28.0

Heavy Atoms 68.0

Ring Count 3.0

Amide Bonds 8.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0150383 VERIFIED: YES

Provenance & Taxonomy

OrganismCoreidae [Animal]

FamilyAKH/HRTH/RPCH

Tax ID186376

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone Metabolic

RECORD: Rec_0171174 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0360298 VERIFIED: YES

Provenance & Taxonomy

OrganismCoreidae [Animal]

FamilyScg-AKH

Tax ID186376

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Metabolic regulation Physiological regulation

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour