Peptide Database

Peptide NamePuroindoline-A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC728H1124N202O204S13

DescriptionStandard

        MKALFLIGLLALVASTAFAQYSEVVGSYDVAGGGGAQQCPVETKLNSCRNYLLDRCSTMKDFPVTWRWWKWWKGGCQELLGECCSRLGQMPPQCRCNIIQGSIQGDLGGIFGFQRDRASKVIQEAKNLPPRCNQGPPCNIPGTIGYYW
    

Molecular Weight16386.79 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)4.41

Net Charge (pH 7.4) 4.02

Charge Density (pH 7.0) 0.0298

GRAVY Index-0.17

Hydrophobic Moment 0.58

Boman Index0.07

Instability Index40.86

Aliphatic Index 75.14

Aromaticity 0.1081

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 41075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6503.66

LogP -63.10

H-bond Donors 232.0

H-bond Acceptors 222.0

Rotatable Bonds 529.0

Heavy Atoms 1147.0

Ring Count 31.0

Amide Bonds 164.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0025912 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Toxin Synergistic peptide Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0090353 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Toxin Synergistic peptide Non-hemolytic

TargetA. tumefaciens (Gram-negative)

RECORD: Rec_0279983 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Toxin Synergistic peptide Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0328417 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Toxin Synergistic peptide Non-hemolytic

TargetC. michiganensis (Gram-positive)

RECORD: Rec_0366000 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Toxin Synergistic peptide Non-hemolytic

TargetP. syringae (Gram-negative)