Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC250H393N69O79S9

DescriptionStandard

        MNLLLPCPGDAHGPASCNHGGGLCRMGSCVSGEYVAQYCFEPIILCCKNLSPATTES
    

Molecular Weight5917.79 Da

Isoelectric Point (pI)5.35

Net Charge (pH 7.0)-2.39

Net Charge (pH 7.4) -2.82

Charge Density (pH 7.0) -0.0419

GRAVY Index0.17

Hydrophobic Moment 0.44

Boman Index0.19

Instability Index49.91

Aliphatic Index 71.93

Aromaticity 0.0526

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2297.88

LogP -27.58

H-bond Donors 83.0

H-bond Acceptors 88.0

Rotatable Bonds 184.0

Heavy Atoms 407.0

Ring Count 10.0

Amide Bonds 60.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425998 VERIFIED: NO

Provenance & Taxonomy

OrganismLonchura striata domestica [Animal]

FamilyBeta-defensin; Defensin

Tax ID299123

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

MethodQualitative functional evidence