Peptide Database

Peptide Namecycloviolacin O15

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC127H198N32O39S5

DescriptionStandard

        GLVPGETCFTGKCYTPGCSCSYPLCKKN
    

Molecular Weight2957.45 Da

Isoelectric Point (pI)8.39

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.42

Charge Density (pH 7.0) 0.0610

GRAVY Index-0.15

Hydrophobic Moment 0.27

Boman Index0.08

Instability Index20.78

Aliphatic Index 38.21

Aromaticity 0.1071

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1122.71

LogP -13.68

H-bond Donors 43.0

H-bond Acceptors 46.0

Rotatable Bonds 90.0

Heavy Atoms 203.0

Ring Count 6.0

Amide Bonds 28.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0168516 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Nematocidal Anthelmintic

TargetHaemonchus contortus

Activity0.38

MethodIC50

RECORD: Rec_0192894 VERIFIED: YES