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MYP_057074
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Basic Information
Antimicrobial peptide Pxt-2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C73H126N18O15
Standard
Sequence
FIGALLRPALKLLA
Physicochemical Analysis
1495.89 Da
11.00
1.76
1.55
0.1257
1.52
0.61
0.45
32.36
188.57
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
520.75
-0.19
18.0
17.0
48.0
106.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0339454 VERIFIED: YES
Provenance & Taxonomy
Xenopus tropicalis [Animal]
8364
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-negative bacteria: Escherichia coli DH5α
50 μg/mL
MIC
PMID25312021;26802742 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25312021/
RECORD: Rec_0367101 VERIFIED: YES
Provenance & Taxonomy
Xenopus tropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NBRC 14237
12.5 μM
MIC
PMID26802742;25312021 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26802742/
RECORD: Rec_0370615 VERIFIED: YES
Provenance & Taxonomy
Xenopus tropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-positive
Staphylococcus aureus
6.5 μM
MIC
RECORD: Rec_0373150 VERIFIED: YES
Provenance & Taxonomy
Xenopus tropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus JCM 2151
9.7 μg/mL
MIC
PMID26802742;25312021 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26802742/
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