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MYP_057074
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Basic Information
Antimicrobial peptide Pxt-2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C73H126N18O15
Standard
Sequence
FIGALLRPALKLLA
Physicochemical Analysis
1495.89 Da
11.00
1.76
1.55
0.1257
1.52
0.61
0.45
32.36
188.57
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
520.75
-0.19
18.0
17.0
48.0
106.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0080150 VERIFIED: YES
Provenance & Taxonomy
Xenopus tropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa NBRC 12582
50 μM
MIC
PMID26802742;25312021 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26802742/
RECORD: Rec_0115088 VERIFIED: YES
Provenance & Taxonomy
Xenopus tropicalis [Animal]
8364
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus JCM 2151
9.7 μg/mL
MIC
PMID25312021;26802742 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25312021/
RECORD: Rec_0134929 VERIFIED: YES
Provenance & Taxonomy
Xenopus tropicalis [Animal]
8364
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
6.5 μM
MIC
PaperIdentification of novel peptides from amphibian (Xenopus tropicalis) skin by direct tissue MALDI-MS analysis
RECORD: Rec_0152458 VERIFIED: YES
Provenance & Taxonomy
Xenopus tropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli DH5alpha
50 μg/mL
MIC
PMID26802742;25312021 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26802742/
RECORD: Rec_0152654 VERIFIED: YES
Provenance & Taxonomy
Xenopus tropicalis [Animal]
8364
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
Rat erythrocytes
PMID25312021;26802742 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25312021/
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