Peptide Database

Peptide NameC(4-21)W2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC111H188N38O22

DescriptionStandard

        RWLRKIRRWRPKVTITIQ
    

Molecular Weight2406.92 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.3755

GRAVY Index-0.95

Hydrophobic Moment 0.76

Boman Index-0.48

Instability Index119.02

Aliphatic Index 102.78

Aromaticity 0.1111

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1025.90

LogP -5.96

H-bond Donors 40.0

H-bond Acceptors 29.0

Rotatable Bonds 80.0

Heavy Atoms 171.0

Ring Count 5.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0360451 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli O78

Activity8.3 ± 2.9 μM

MethodMIC