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MYP_057051
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Basic Information
A2 (IG-19 analogs)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
19 amino acids
C112H197N35O22
Standard
Sequence
IGKKFKRIVQRIKKFLRNL
Physicochemical Analysis
2385.98 Da
12.00
7.76
7.54
0.4082
-0.50
1.02
-0.34
21.95
117.89
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
989.10
-5.30
36.0
30.0
89.0
169.0
2.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0264659 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis (KCTC 3068)
2 μM
MIC
PaperProkaryotic selectivity and LPS-neutralizing activity of short antimicrobial peptides designed from the human antimicrobial peptide LL-37. Peptides. 2012 Jun;35(2):239-247. doi: 10.1016/j.peptides.2012.04.004. PMID: 22521196. PMID22521196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22521196/
RECORD: Rec_0330987 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium KCTC 1926
8 μM
MIC
PMID22521196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22521196/
RECORD: Rec_0342792 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PaperProkaryotic selectivity and LPS-neutralizing activity of short antimicrobial peptides designed from the human antimicrobial peptide LL-37. Peptides. 2012 Jun;35(2):239-247. doi: 10.1016/j.peptides.2012.04.004. PMID: 22521196. PMID22521196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22521196/
RECORD: Rec_0376271 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PaperProkaryotic selectivity and LPS-neutralizing activity of short antimicrobial peptides designed from the human antimicrobial peptide LL-37. Peptides. 2012 Jun;35(2):239-247. doi: 10.1016/j.peptides.2012.04.004. PMID: 22521196. PMID22521196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22521196/
RECORD: Rec_0386436 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBC
11.2 μM
Hemolysis
PMID22521196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22521196/
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