Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC381H613N103O123S12

DescriptionStandard

        MKTLSVFVAVAIVLTVMCSQQSSAVPVLQGEELEETIFFANPGGAMDETVMDSMKTLSNNRQKRGLDCEFCCRDGGCGICCSW
    

Molecular Weight8989.34 Da

Isoelectric Point (pI)4.50

Net Charge (pH 7.0)-4.55

Net Charge (pH 7.4) -4.89

Charge Density (pH 7.0) -0.0548

GRAVY Index0.20

Hydrophobic Moment 0.47

Boman Index0.11

Instability Index44.75

Aliphatic Index 76.27

Aromaticity 0.0602

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3628.88

LogP -40.88

H-bond Donors 131.0

H-bond Acceptors 131.0

Rotatable Bonds 301.0

Heavy Atoms 619.0

Ring Count 8.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006877 VERIFIED: NO

Provenance & Taxonomy

OrganismGouania willdenowi [Animal]

FamilyHepcidin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial

MethodQualitative functional evidence