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MYP_057039
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Basic Information
D5R (Derived from HD5)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
26 amino acids
C126H214N44O39
Standard
Sequence
ATYRTGRATRESLSGVEISGRLYRLR
Physicochemical Analysis
2969.32 Da
11.34
3.80
3.60
0.1461
-0.72
0.60
-0.33
15.57
78.85
0.0769
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1398.66
-17.38
55.0
43.0
100.0
209.0
2.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0257027 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Saccharomyces cerevisiae (BY4741)
100 μM
MIC
PMID26206286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26206286/
RECORD: Rec_0306466 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acylation (Conjugated with lauric acid)
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus (NCTC 8530)
20 μM
MIC
PMID26206286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26206286/
RECORD: Rec_0314778 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acylation (Conjugated with lauric acid)
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa (NCTC 6750)
10 μM
MIC
PMID26206286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26206286/
RECORD: Rec_0323360 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acylation (Conjugated with myristic acid)
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli (MG 1655)
5 μM
MIC
PMID26206286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26206286/
RECORD: Rec_0331560 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human red blood cells
PMID26206286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26206286/
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