Peptide Database

Peptide NameNeocarzinostatin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length137 amino acids

Chemical FormulaC591H944N166O195S5

DescriptionStandard

        MPARRIRLATAGVLGAAAALGALAASPAAAAAPAVTVTPSTGLADGQTVSVSGSGYVAGSAIGVSECVRDTVCAEDTVHTTAAADGTFSAQYVARKQFQATDWSTGQTITVDCAVEQCQIVAWEQEIGPIAQPISFG
    

Molecular Weight13655.14 Da

Isoelectric Point (pI)4.50

Net Charge (pH 7.0)-5.43

Net Charge (pH 7.4) -5.78

Charge Density (pH 7.0) -0.0397

GRAVY Index0.33

Hydrophobic Moment 0.48

Boman Index0.21

Instability Index29.82

Aliphatic Index 84.96

Aromaticity 0.0511

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5688.05

LogP -73.34

H-bond Donors 201.0

H-bond Acceptors 196.0

Rotatable Bonds 430.0

Heavy Atoms 957.0

Ring Count 16.0

Amide Bonds 145.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416267 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces sp. WAC 06738 [Bacterium]

FamilyNeocarzinostatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal