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MYP_057017
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Basic Information
THP-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
40 amino acids
C190H320N58O51S6
Standard
Sequence
GKREKCLRRNGFCAFLKCPTLSVISGTCSRFQVCCKTLLG
Physicochemical Analysis
4425.32 Da
9.61
6.70
6.40
0.1675
0.13
0.46
-0.06
42.55
75.50
0.0750
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1785.97
-20.05
71.0
64.0
150.0
305.0
4.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012602 VERIFIED: YES
Provenance & Taxonomy
Meleagris gallopavo [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfide bonds
Bio-Activity Profile
Antimicrobial Antifungal
S. enteriditis
8 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
RECORD: Rec_0033666 VERIFIED: YES
Provenance & Taxonomy
Wild turkey [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID7964174 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7964174/
RECORD: Rec_0154877 VERIFIED: YES
Provenance & Taxonomy
Meleagris gallopavo [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfide bonds
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli
8 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
RECORD: Rec_0157515 VERIFIED: YES
Provenance & Taxonomy
Meleagris gallopavo [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfide bonds
Bio-Activity Profile
Antimicrobial Antifungal
P-multocida
>16 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
RECORD: Rec_0159402 VERIFIED: YES
Provenance & Taxonomy
Meleagris gallopavo [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfide bonds
Bio-Activity Profile
Antimicrobial Antifungal
B. avium
8 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
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