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MYP_057010
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Basic Information
Hexarelin
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-wrinkle
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Collagen boosting
Standard
6 amino acids
C46H55N11O7
Standard
Sequence
HWAWFK
Physicochemical Analysis
874.00 Da
8.76
0.85
0.59
0.1411
-0.72
0.23
0.26
-46.57
16.67
0.5000
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
295.10
1.63
11.0
9.0
23.0
64.0
6.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0351723 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Growth hormone secretagogue-derived peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Biotinylation
Bio-Activity Profile
Anti-aging Anti-wrinkle Collagen boosting
Human adult primary epidermal keratinocyte (HEKa) (In vitro)
Immunostaining; Histology
PaperAnti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression PMID31861912 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31861912/
RECORD: Rec_0372718 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GHRH/CRF
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
D-residue notation at positions 2, 5; Mixed L/D stereochemistry with D-annotated positions 2, 5
Bio-Activity Profile
Endocrine
Radioimmunoassay
(Dose i/v injected)Dog plasma, in vivo; 7200 s
PMID8545255 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8545255/
RECORD: Rec_0417655 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Growth hormone secretagogue-derived peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Biotinylation
Bio-Activity Profile
Anti-aging Anti-wrinkle Collagen boosting
Asian females with face wrinkles (40-60 years) (Randomized clinical trial)
Immunostaining; Histology
PaperAnti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression PMID31861912 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31861912/
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