Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC357H580N108O107S12

DescriptionStandard

        MKTFPVAVAVAVVLTFICVQQSSAVPAAEVGDLTRVSGCPDGRDDAGEMPYNNREKRGVRCKFCCNCCTRGVCGLCCRF
    

Molecular Weight8481.86 Da

Isoelectric Point (pI)8.38

Net Charge (pH 7.0)2.41

Net Charge (pH 7.4) 2.03

Charge Density (pH 7.0) 0.0305

GRAVY Index0.17

Hydrophobic Moment 0.53

Boman Index0.01

Instability Index42.99

Aliphatic Index 68.99

Aromaticity 0.0633

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 2115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3447.71

LogP -40.70

H-bond Donors 130.0

H-bond Acceptors 122.0

Rotatable Bonds 274.0

Heavy Atoms 584.0

Ring Count 9.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177076 VERIFIED: NO

Provenance & Taxonomy

OrganismCyclopterus lumpus [Animal]

FamilyHepcidin

Tax ID8103

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal