Peptide Database

Peptide NameCalcitonin gene-related peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC164H270N50O50S2

DescriptionStandard

        SCNTATCVTHRLAGLLSRLGGVVKSNFVPTNVGSQAF
    

Molecular Weight3806.33 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)2.53

Net Charge (pH 7.4) 2.24

Charge Density (pH 7.0) 0.0683

GRAVY Index0.35

Hydrophobic Moment 0.64

Boman Index0.15

Instability Index19.67

Aliphatic Index 89.46

Aromaticity 0.0541

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1614.83

LogP -22.24

H-bond Donors 59.0

H-bond Acceptors 56.0

Rotatable Bonds 122.0

Heavy Atoms 266.0

Ring Count 4.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010812 VERIFIED: YES

Provenance & Taxonomy

OrganismUnknown [Animal]

FamilyCalcitonin gene-related peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0171671 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyCalcitonin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide2-7

Bio-Activity Profile

Function

Hormone Calcium-regulatory peptide

RECORD: Rec_0199999 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/