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MYP_056978
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Basic Information
Pardaxin-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
33 amino acids
C154H248N36O45
Standard
Sequence
GFFALIPKIISSPLFKTLLSAVGSALSSSGGQE
Physicochemical Analysis
3323.83 Da
8.59
0.77
0.56
0.0232
0.75
0.50
0.37
39.52
112.42
0.0909
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1271.21
-13.02
44.0
46.0
108.0
235.0
5.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0353846 VERIFIED: YES
Provenance & Taxonomy
Epinephelus nebulosus [Animal]
Epinephelus nebulosus
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HeLa
50 μg/mL
Cytotoxicity assay
PaperTruncated antimicrobial peptides from marine organisms retain anticancer activity and antibacterial activity against multidrug-resistant Staphylococcus aureus PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0354448 VERIFIED: YES
Provenance & Taxonomy
Epinephelus nebulosus [Animal]
Epinephelus nebulosus
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HeLa
25 μg/mL
Cytotoxicity assay
PaperTruncated antimicrobial peptides from marine organisms retain anticancer activity and antibacterial activity against multidrug-resistant Staphylococcus aureus PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0367008 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 45.5%, E 0.0%, T 42.4%, C 12.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antibacterial Toxic Antimicrobial Hemolytic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0367274 VERIFIED: YES
Provenance & Taxonomy
Epinephelus nebulosus [Animal]
Epinephelus nebulosus
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HeLa
12.5 μg/mL
Cytotoxicity assay
PaperTruncated antimicrobial peptides from marine organisms retain anticancer activity and antibacterial activity against multidrug-resistant Staphylococcus aureus PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0372257 VERIFIED: YES
Provenance & Taxonomy
Pardachirus marmoratus [Animal]
Pardaxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPardaxin Pa4 Evidence URLhttps://www.uniprot.org/uniprotkb/P81861/entry
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