‹ ›
MYP_056978
← PREVIOUS NEXT → BACK
Basic Information
Pardaxin-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
33 amino acids
C154H248N36O45
Standard
Sequence
GFFALIPKIISSPLFKTLLSAVGSALSSSGGQE
Physicochemical Analysis
3323.83 Da
8.59
0.77
0.56
0.0232
0.75
0.50
0.37
39.52
112.42
0.0909
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1271.21
-13.02
44.0
46.0
108.0
235.0
5.0
33.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0205894 VERIFIED: YES
Provenance & Taxonomy
Pardachirus marmoratus [Animal]
Pardaxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Antimicrobial
SCC-4
5-25 μg/mL
PaperIn Vitro and in Vivo Anticancer Activity of Pardaxin against Proliferation and Growth of Oral Squamous Cell Carcinoma PMID26703631 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26703631/
RECORD: Rec_0206600 VERIFIED: YES
Provenance & Taxonomy
Pardachirus marmoratus [Animal]
pardaxin family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Toxin Venom pardaxin family
PaperPDB 2KNS structural record; NMR; chain A; residues 1-33
RECORD: Rec_0222790 VERIFIED: YES
Provenance & Taxonomy
Pardachirus marmoratus [Animal]
Red Sea Mosessole
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HT-1080
15.40 μg/mL
IC50
PMID22073006 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22073006/
RECORD: Rec_0223409 VERIFIED: YES
Provenance & Taxonomy
Pardachirus marmoratus [Animal]
Red Sea Mosessole
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HT-1080
15.74 μg/mL
IC50
PMID22073006 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22073006/
RECORD: Rec_0233133 VERIFIED: YES
Provenance & Taxonomy
Pardachirus marmoratus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-MDV Replication inhibition
Foot-and-Mouth Disease virus(FMDV) | BHK-21 cells
2.4±0.1 μg/mL
IC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperGrouper (Epinephelus coioides) antimicrobial peptide epinecidin-1 exhibits antiviral activity against foot-and-mouth disease virus in vitro. | Huang HN, Pan CY, Chen JY. | Peptides. 2018 Aug;106:91-95. | DOI:10.1016/j.peptides.2018.07.003 | PMID:30012343 PMID30012343 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30012343/
FIRST PREV 1 ... 3 4 5 6 7 ... 10 NEXT LAST
Showing 5 records on this page · Page 5 of 10