‹ ›
MYP_056961
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
50 amino acids
C242H382N76O76S5
Standard
Sequence
YRQSMNQGSRSTGCRFGTCTMQKLAHQIYQFTDKDKDGMAPRNKISPQGY
Physicochemical Analysis
5732.41 Da
9.70
4.82
4.53
0.0965
-1.15
0.60
-0.27
44.77
27.40
0.1000
4470.00
4595.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2531.15
-33.25
90.0
87.0
194.0
399.0
8.0
57.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0003570 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
14-19
Bio-Activity Profile
Drug Delivery Vehicle Blood-Brain Barrier
PaperBrainpeps: the blood-brain barrier peptide database PMID22205159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22205159/
RECORD: Rec_0041472 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; Rattus norvegicus [Animal]
Calcitonin family
9606; 10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
14-19
Bio-Activity Profile
Hypotensive Vasodilatory
Wistar-Kyoto rat plasma
Radioimmunoassay
1.19 ± 0.09 min
PaperSynthetic human adrenomedullin and adrenomedullin 15-52 have potent short-lived vasodilator activity in the hindlimb vascular bed of the cat
RECORD: Rec_0110802 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Calcitonin
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
14-19
Bio-Activity Profile
Hypotensive
0.003 μM
Radioimmunoassay
Rat(SHR) plasma, in vivo; 63 s
PMID8542672 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8542672/
RECORD: Rec_0115061 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
14-19
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0115703 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Hypotensive
0.003 μM
Radioimmunoassay
Wistar-Kyoto rats, in vivo; 978 s
PMID8542672 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8542672/
1 2 3 NEXT LAST
Showing 5 records on this page · Page 1 of 3