Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length269 amino acids

Chemical FormulaC1295H2015N343O360S8

DescriptionStandard

        TAAIDTVASIDYSLVGPPVVTAQYLDVNLKGEVFSRAHRAPAPFSAPALALPTERGRMVYLGVSSYFFNTAGVVYQAAGLLVFNITNDMFPKEGFFHLNTSAFSHFIPQVSGLLPLRLTTPSAPFLTVAPRGLELALVMDIQAYASLPSASLAPLFLLPGPGSTHEAPQPCAAAGGAPLPPPQRVWSLGHPVLLPPTSGCHLLCFSDRLKKGFSLPLPKHVQLSGCSLQPRQVSDTGWGARTPSGLGGLRGSFPSPVEGESPLERTRCL
    

Molecular Weight28405.45 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.98

Net Charge (pH 7.4) 2.33

Charge Density (pH 7.0) 0.0111

GRAVY Index0.18

Hydrophobic Moment 0.63

Boman Index0.19

Instability Index42.00

Aliphatic Index 91.41

Aromaticity 0.0855

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20190.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081295 VERIFIED: NO

Provenance & Taxonomy

OrganismCrocodylus porosus (Saltwater crocodile) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria