Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC436H691N107O117S3

DescriptionStandard

        MRTKQVPVLWACFLLWSLYIASSQTVYPGITARITQRALDYGLQVGMKVLEQLAKEIVIPDLNGSESLKFLKIDYVKYNFSK
    

Molecular Weight9399.99 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)3.49

Net Charge (pH 7.4) 3.23

Charge Density (pH 7.0) 0.0426

GRAVY Index0.16

Hydrophobic Moment 0.71

Boman Index0.13

Instability Index28.16

Aliphatic Index 111.71

Aromaticity 0.1220

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3622.35

LogP -24.19

H-bond Donors 127.0

H-bond Acceptors 124.0

Rotatable Bonds 312.0

Heavy Atoms 663.0

Ring Count 15.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390201 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBPI/LBP

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence