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MYP_056928
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Basic Information
Cter B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
31 amino acids
C141H227N35O42S6
Standard
Sequence
GVPCAESCVWIPCTVTALLGCSCKDKVCYLN
Physicochemical Analysis
3276.91 Da
6.03
-0.30
-0.60
-0.0096
0.77
0.25
0.27
37.21
94.19
0.0645
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1205.41
-11.46
47.0
48.0
100.0
224.0
5.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0155982 VERIFIED: NO
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
Backbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21194241 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21194241/
RECORD: Rec_0202939 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Cytotoxic Antifungal Anti-Gram-negative
Pseudomonas aeruginosa
20 μM
MIC
PaperPubMed PMID 2341998 | PubMed PMID 8286697 | PubMed PMID 6000000 | Gilding et al., 2016 PMID2341998;8286697;6000000;23419988;28669;76000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2341998/
RECORD: Rec_0264682 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Cytotoxic Antifungal Anti-Gram-positive
Staphylococcus aureus
160 μM
MIC
PaperPubMed PMID 2341998 | PubMed PMID 8286697 | PubMed PMID 6000000 | Gilding et al., 2016 PMID2341998;8286697;6000000;23419988;28669;76000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2341998/
RECORD: Rec_0268067 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Cytotoxic Antifungal Anti-Gram-negative
Pseudomonas aeruginosa
5 μM
MIC
PaperPubMed PMID 2341998 | PubMed PMID 8286697 | PubMed PMID 6000000 | Gilding et al., 2016 PMID2341998;8286697;6000000;23419988;28669;76000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2341998/
RECORD: Rec_0276859 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Cytotoxic Antifungal Anti-Gram-negative
Escherichia coli
80 μM
MIC
PaperPubMed PMID 2341998 | PubMed PMID 8286697 | PubMed PMID 6000000 | Gilding et al., 2016 PMID2341998;8286697;6000000;23419988;28669;76000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2341998/
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