Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length251 amino acids

Chemical FormulaC1277H1945N287O378S10

DescriptionStandard

        SFHVFYSILYLALPTTLTAVMPVDDLAEVDYSLNSLPAVFQPFIDLDLKGTVFPAGNYTGSPYKAAPFTIPEQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNIGTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIVTLEQDSFTVDIQGSMEVLAVLPDSTPQSLFTMNIAANTSISLNIFNQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANGKSVFQTISLK
    

Molecular Weight27686.45 Da

Isoelectric Point (pI)4.22

Net Charge (pH 7.0)-14.36

Net Charge (pH 7.4) -14.75

Charge Density (pH 7.0) -0.0572

GRAVY Index0.39

Hydrophobic Moment 0.55

Boman Index0.28

Instability Index45.94

Aliphatic Index 99.08

Aromaticity 0.1315

Extinction Coeff. Reduced 19370.00

Extinction Coeff. Oxidized 19495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320107 VERIFIED: NO

Provenance & Taxonomy

OrganismNeodrepanis coruscans [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria